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June 7, 2001 - Zyban: General Information

June 7, 2001 - Zyban: General Information

Zyban or bupropion hydrochloride is a non-nicotine oral aid to smoking cessation. Bupropion hydrochloride is also prescribed for depression. It is not exactly known exactly how the drug works as a smoking deterrent. It is used to help in smoking cessarion treatment that consists of behavioral interventions, counseling and other support services.


Any of the following may be reason to choose a different drug. Inform your doctor before starting therapy.

Allergic to bupropion

Using other bupropion products or monoamine oxidase inhibitors (MAOI) at the same time as bupropion

History of a seizures disorder

History of anorexia nervosa or bulimia

Common side effects

You may experience the following side effects with the use of this drug:

Nausea or vomiting

Loss of appetite


Dry mouth

Weight loss

Increased sweating






Skin rash or itching


Ringing in the ears






Increased heart rate

Blurred vision

Taste changes

Life-Threatening Symptoms


Possible Overdose Symptoms

Increased heart rate

Nausea or vomiting


Loss of consciousness


There is a 1/1000 chance that patients taking Zyban will have a seizure. Discuss this with your physician. Predisposing factors that may increase the risk of seizures associated with bupropion therapy include a prior history of seizures, a history of head trauma, CNS tumor, or concomitant use of any drug that lowers the seizure threshold, such as MAO inhibitors, antipsychotics, steroids, anorexiants, or theophylline. Bupropion is generally started 7 days before the date on which smoking will be discontinued. It is important to also participate in a smoking cessation program to ensure maximum benefit from using this medication.

Drug Dependency

   Wellbutrin is likely to have a low drug abuse potential. There have been few reported cases of drug dependence and withdrawal symptoms.

Pregnancy Warnings

   There are no adequate studies of fetal harm in pregnant women. If you are pregnant or plan to be, discuss this with your physician before initiating therapy.

Nursing Mothers

   Because of the risk of potential harm to the newborn, avoid using this drug while breastfeeding. If therapy is necessary, avoid breastfeeding while on this drug.

Prolonged Use

   Usage rarely lasts beyond the manufacturer recommended 7 to 12 weeks.

Discontinuing Therapy

   Only discontinue therapy on the advice of your physician.

Operating a Vehicle or Heavy Machinery

   This drug may produce side effects that impair your mental alertness, such as dizziness and confusion. Avoid such activities if you feel these symptoms. Avoid consuming alcohol or other CNS depressants while taking this drug. They may intensify these side effects.

If you or a loved one has suffered an injury as a result of taking any drug or supplement, call Law Offices of Robert Dourian now at 800-790-8856 or CLICK HERE TO SUBMIT A SIMPLE CASE FORM. The initial consultation is free of charge, and if we agree to review your case, we will work on a contingent fee basis, which means we get paid for our services only if there is a monetary award or recovery of funds. Don't delay! You may have a valid claim and be entitled to compensation for your injuries, but a lawsuit must be filed before the statute of limitations expires.

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